Main Menu

Folate and B Vitamins Don't Cut Pre-colorectal Cancer Risk


According to a study in the Journal of the National Cancer Institute, the combination of folic acid, vitamin B6 and vitamin B12 has no effect on reducing the risk of developing colorectal adenoma a precursor to colorectal cancer.

This runs counter to prior pre-clinical and epidemiological studies that suggested that folate and B vitamins had some effect against the disease.

Seeking to determine the possible effects of folic acid, vitamin B6 and vitamin B12 on the risk of colorectal adenoma, Yiqing Song, M.D., of Harvard Medical School and colleagues carried out a retroprospective study in the Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS).

WAFACS was a randomized, double-blind, placebo-controlled trial with 5,442 female health professionals at high risk for cardiovascular disease. It took place between April 1998 and July 2005.

WAFACS participants were randomly assigned to:

1. A combination of folic acid, vitamin B6 and vitamin B12
2. Placebo.

Saying that more research was needed to confirm their study, the researchers none the less wrote that their findings "do not support recommending B-vitamin supplementation for the prevention of colorectal adenomas."

Source: Medical News Today

Those who liked this article also liked...

  • addiction news thumbnailThe effects of Crohn’s disease, and even the treatments, can make it difficult for your body to absorb vitamins and minerals. However, if you take the right supplements you can ensure that you stil…
  • addiction news thumbnailDubbed the “super-veggies,” the cruciferous, or cabbage vegetable family has high nutritional value in each one of its several super items. These disease-fighting, vitamin and fiber-rich phytochem…
  • addiction news thumbnailBesides being a delicious seasoning used in cooking, garlic is widely recognized for its many health benefits. For thousands of years, garlic has been used in many cultures around the world both in c…
  • addiction news thumbnailLutein, a carotenoid vitamin, is a compound found in various foods including fruits and vegetables. Although it is known as “the eye vitamin,” lutein helps prevent several different diseases and …


This information is solely for informational and educational purposes only. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of or the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Be aware that many of the techniques and remedies published on this site have not been evaluated in scientific studies. Often, only limited information is available about their safety and effectiveness. Use of these remedies in connection with other medications can cause severe adverse reactions. It is always best to speak with your primary health care provider before engaging in any form of self treatment. Additional information contained in our Legal Statement

Daily Videos

In order to view the content on this page, you will need the latest version of Adobe’s Flash Player. Click here to download it. Social


Do You Take Supplements To Stay Healthy?
Yes, I take a multivitamin
Yes, I take individual vitamins
Yes, I take herbal supplements
Yes, I take various supplements
No, but I should
No, I don't believe in them
Total votes: 7086